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According to the power calculation, the first 80 participants underwent MRI

Rushing the schedule increases the risk of nausea, vomiting, and other gastrointestinal side effects

Snap closures, magnetic lids, tamper-evident seals, and secure flaps for controlled access

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Moreover, in these NI trials, it is unclear how the specific subgroups effects should have been interpreted with respect to the NI margins which were defined for the overall population, or whether subgroup-specific margins should have been employed

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