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GLP-1 induced activation of PKA increases Pdx1 expression and translocation of Pdx1 to the nucleus, where Pdx1 binds to the insulin promoter to initiate insulin expression and synthesis (Figure 5) [490,524]
( C ) Body weights of individual cycled mice 14 days after each cycle
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2010;298:G60814
Novo expects an approval decision from the U.S
