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However, it is widely prescribed off-label by endocrinologists and specialist physicians in Pakistan for medically supervised weight management, as its appetite-suppressing and gastric-slowing effects lead to significant weight reduction in many patients

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Checking first helps ensure the supplement fits safely into your routine and gives you peace of mind when using it alongside other products

The dual GIP/GLP-1 receptor agonism of tirzepatide appears to be the primary protective factor, as GIP receptor activation may counterbalance some of the autonomic and vestibular effects of GLP-1 receptor stimulation

By acting on both GLP-1 and GIP receptors, Tirzepatide helps control blood sugar more broadly, stimulates insulin release, reduces glucagon release, slows down foods movement through the gut, and decreases appetite and food intake

2013;8(4):e61965 (in English)
