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Side effects that have been reported Based on the ingredients commonly found in these patches, potential issues include: Skin reactions redness, itching, or contact dermatitis from adhesives or active ingredients Digestive upset berberine is known to cause diarrhoea, constipation, and stomach cramps, even orally Garcinia cambogia concerns some reports have linked it to liver problems, though this is rare and mainly documented with oral supplements Unknown interactions if you take medication for blood pressure, diabetes, or mental health conditions, herbal ingredients in patches could interact in unpredictable ways Both the MHRA and the US FDA have warned that some weight loss supplements contain undisclosed pharmaceutical ingredients substances not listed on the label that could include prescription drugs or banned compounds