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Safety and pharmacokinetics of single and multiple ascending doses of the novel oral human GLP-1 analogue, oral semaglutide in healthy subjects and subjects with type 2 diabetes

If donating plasma is a personal priority, discuss with your prescribing provider whether a short pause in GLP-1 therapy might be medically appropriate for you

Results In all, 39 pwIIH (mean age 33.6 years [SD 8.0], 92.3% female, median BMI 36.3 kg/m 2 [IQR 31.438.3]) were included, with 13 pwIIH being treated with GLP-1-RAs and remaining adherent to the treatment throughout the study

United States FDA status: Not approved

As our understanding of the estrogen-GLP-1 interaction deepens, these therapies are likely to become increasingly central to women's health care during the menopausal transition

The exact clinical titration protocol will be finalized after Phase 3 completion