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Protein intakes of 1.2 to 1.6 grams per kilogram body weight help preserve lean mass during weight loss while supporting satiety beyond what tirzepatide provides alone

Tirzepatide, acting on GIP and GLP-1 receptors, regulates glucose, insulin, and glucagon while boosting lipid regulation and reducing food intake

Data were extracted from the intention-to-treat population, which included all randomly assigned participants who received at least one dose of the study medication

Long-term considerations for autoimmune patients on tirzepatide Duration of treatment Metabolic research suggests that tirzepatide weight loss benefits reverse after discontinuation , with most patients regaining significant weight within 12 to 18 months of stopping

SOURCES: FDA announcement, Dec

It also provides valuable data for provider conversations about dose adjustments