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[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Johnson E.C., Demontis D., Thorgeirsson T.E., Walters R.K., Polimanti R., Hatoum A.S., Sanchez-Roige S., Paul S.E., Wendt F.R., Clarke T.-K., et al

It has effectively reduced HbA1c levels and optimized postprandial glucose regulation

The study provides a detailed mechanistic insight into the interplay between metabolic reprogramming, protein stability, and drug response in the context of obesity and cancer

34:e3061 [PubMed: 30109766] 359

Research in this area is needed, but the mechanistic rationale is sound
