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Other Metabolic Benefits In the T2D trial, there were also dose-response reductions in HbA1c: retatrutide 12 mg reduced HbA1c by 2.16% at 36 weeks, corresponding to an estimated difference from dulaglutide 1.5 mg of -0.80% (95% CI: -1.16, -0.44)

For UC patients, exercise should be tailored to current disease activitygentle activities like walking or swimming may be more appropriate during flares, whilst more intensive exercise can be pursued during remission

Although rates of acute pancreatitis have been low and similar between GLP-1 agonists and placebo in studies, caution is still warranted since acute pancreatitis carries a risk of recurrencewhich can turn into chronic pancreatitiswhich can increase risk of pancreatic cancer

Peptides can aggregate at high concentrations, improper buffer conditions, or due to an imbalance of hydrophobic and hydrophilic properties

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Obesity Medicine Association