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Frequently Asked Questions Is semaglutide safe for long-term weight loss, or should I only use it short-term

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Early attempts to develop GLP-1 therapies faced a critical obstacle: the hormone degrades rapidly in the bloodstream

Adipose tissue is metabolically active and secretes pro-inflammatory cytokines such as TNF-alpha and interleukin-6
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[18] Lifestyle strategies, including physical exercise, caloric restriction, intermittent fasting, and low-glycemic diets, can also improve metabolic health and insulin responsiveness, reducing neuronal hyperexcitability
