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AE outcomes included all participants in the study to provide comprehensive safety reporting, while all other outcomes were reported for those who completed the study and had analyzable paired measures (that is, for both semaglutide and placebo)

The peptide compound itself, combined with the injection's physical pressure, can trigger localized irritation in nerve endings near the injection site

A healthcare provider decides the right dose for each person based on their needs

She said about 20% of patients who undergo the procedure later develop problems with alcohol or other substance use

The colon responds by secreting thick, stringy fluids to protect itself from the harsh fermentation byproducts

Weight loss is associated with improvements in biomarkers, MASLD severity, and a lower risk of MASH, but its effect on long-term health is not known