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[DOI] [PMC free article] [PubMed] [Google Scholar] 204.Look A.R.G., Wadden T.A., West D.S., Delahanty L., Jakicic J., Rejeski J., Williamson D., Berkowitz R.I., Kelley D.E., Tomchee C., et al
A patient with established cardiovascular disease might continue low-dose Metformin indefinitely for its protective effects
Conversely, constipation can cause excessive straining during bowel movements, leading to tension in the pelvic floor muscles
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Instead, the next step is to consult with a specialist who can refine your plan
