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Conclusion GLP-1RAs show significant promise as a potential disease-modifying therapy for neurodegenerative and inflammatory eye diseases, acting through both systemic metabolic improvements and direct ocular mechanisms, representing a paradigm shift beyond their metabolic indications.

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This review explores the immunomodulatory impact of gut-derived metabolites in IS, with a focus on short-chain fatty acids (SCFAs) and other bioactive substances

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