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Description
Potential Mechanisms Behind Temperature Sensitivity With GLP-1 Use GLP-1 receptor signaling influences brown adipose tissue activation and core body temperature regulation
Participants were randomized in a 2:1:1:1:1:2:2 ratio to once-weekly subcutaneous retatrutide at 1 mg, 4 mg, 8 mg, or 12 mg, or placebo, over a 48-week treatment period
Schedule: First injection timed so that days 2 and 3 fall on low-obligation days
Stifles Inflammation May target chronic inflammation to support joint health and reduce pain
DAPI, 4,6-diamidino-2-phenylindole
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