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However, to date, this hypothesis remains inconclusive because mice lacking GLP-1 receptors (GLP-1Rs) responded similarly to controls after vertical sleeve gastrectomy

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Among GLP-1 users, the 18-month risk of ION was about 8.5 cases per 10,000 people, compared with 5.5 cases per 10,000 among patients taking SGLT2 inhibitors