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Diabetes 64 , 23462351 (2015)
Nevertheless, unimolecular GIPGLP-1 co-agonism is an effective therapy for type 2 diabetes, associated with weight loss and reduction of fat mass, in rats, mice, monkeys and humans [66]
doi: 10.2337/dci19-0014
In the case of GLP-1 medications, this could include adjustments like adding B12 for potential energy support or modifying the formulation to help with nausea management, both of which are common and well-established practices in compounding
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The GIP component may also help preserve lean mass through its effects on insulin sensitivity in muscle tissue
