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Tirzepatide significantly outperformed dulaglutide, semaglutide, degludec, and glargine in terms of its effects on postprandial and fasting blood glucose levels as well as the likelihood that patients using it would experience a decrease in HbA1c [8-10]

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No one has run the cleaner experiment of matching the exact pounds lost across methods, but the pattern keeps repeating: how much muscle you lose tracks how much weight you lose, not which method got you there

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