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The degree of this effect varies between individuals based on semaglutide dose, duration of therapy, and your genetic predisposition to peptide sensitivity

Less fluid in the gut means: Less lubrication Firmer stools Slower transit Dehydration also concentrates electrolytes like calcium, which can have constipating effects

Reconstitution, injection preparation, and actual administration take 5 to 15 minutes per dose

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J Mol Endocrinol 59 , R1R10, (2017)

Patients should discuss the risks and symptoms of pancreatitis with their doctor