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If you're post-cholecystectomy and considering GLP-1 therapy, discussing your biomarker profile, genetic predispositions, and current GI symptoms with a qualified healthcare provider helps determine the safest and most effective approach

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Brookshire: Yes, it helps a lot of people lose weight

The observed weight loss might not be as high as with some of the newer injectable GLP-1 medications, he says, but the oral pills offer the potential of having an inexpensive, accessible drug. Both pills must be taken daily, whereas many GLP-1 injections are weekly

The delayed gastric emptying may potentially contribute to changes in the gut microbiome in some individuals

This could eventually help reduce reliance on biopsies, which are invasive and difficult to repeat, and make it easier for clinicians to monitor patients over time