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CrossRef Comparison of Risk Assessment Strategies for Patients with Diabetes Mellitus and Stable Chest Pain: A Coronary Computed Tomography Angiography Study Jia Zhao, Shuo Wang, Pengyu Zhao, Yong Huo, Chunjie Li, Jia Zhou, Pawel Kleczynski Journal of Diabetes Research.2022

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Limited brain penetration of agonists: Studies using fluorescently labelled GLP-1 receptor agonists like semaglutide and liraglutide have shown very limited penetration into most brain regions beyond the circumventricular organs areas where the bloodbrain barrier is less effective and allows the brain to sample blood contents

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Moreover, as we gain a deeper understanding of the mechanisms behind GLP-1, I expect to witness innovative combinations with other therapies

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