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Impact This study provides age- and sex-specific reference values for glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon in children and adolescents

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The standard escalation starts at 2.5mg weekly for the first four weeks

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GLP-1 receptors are expressed in brainstem regions implicated in respiratory rhythmogenesis, and their activation has been shown to stabilize breathing patterns and enhance respiratory drive in preclinical models [35]

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Allergic skin reactions, sometimes temporary, were reported in clinical studies of the drug

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