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For example, many patients prefer virtual consultations due to shorter wait times and easier access

A wave of 2nd generation GLP-1 agonists came to market between 2014-2021, improving clinical outcomes and providing more convenient dosing and administration options

It is majorly found circulating in the blood as GLP-1(7-36) amide that is produced primarily from three tissues of the human body: enteroendocrine L cells in the distal small bowel, cells in the pancreas, and the central nervous system ( Surprisingly, it took approximately 20 years from the discovery of GLP-1 to the authorized approval of worldwide utilized GLP-1 RAs

To view or add a comment, sign in What happens when a clinical trial needs to shift midstream

Compliance with Reporting Guidelines: The systematic review and meta-analysis were conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines

Notably, in the SELECT trial, individuals with obesity with established ASCVD without T2D were treated with semaglutide 2.4 mg/week and demonstrated a weight loss of over 9% (59)