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Description
The SELECT trial results established GLP-1 receptor activation as cardioprotective in ways that previous surrogate marker improvements only suggested

J.CapehornM.CharpentierG.DottaF.HenkelE.LingvayI.et al (2018)

Data collected November and December 2025, six months after the average discontinuation month of five months on the program

When a cardiologist's primary clinical mandate is preventing heart attacks and strokes, and a drug demonstrates 20% reduction in major cardiovascular events, that drug becomes a cardiovascular medicine rather than a metabolic medicine

Injected semaglutide achieves rapid, consistent blood levels that patches have not matched in published studies

The outcome in question was NAION (ICD-10: H47.01)
