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Contribution statement MA contributed to the generation of the results and analysis using the TriNetX platform and took the lead on writing the manuscript

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Br J Clin Pharmacol (2018) 84(10):232535

The hypoglycemic activity of GLP-1 is associated with the stimulation of glucose-dependent insulin secretion, inhibition of glucagon production and regulation of islet cell proliferation, differentiation, and survival

543 The JAK-STAT pathway serves as a hub for cytokine signaling, and inhibitors such as tofacitinib effectively block IL-6- and IL-23-mediated immune cell activation by competitively occupying the ATP binding site of the kinase

One innovative method employs focused ultrasound (FUS) combined with microbubbles to transiently open the BBB, facilitating nanoparticle entry into the CNS [291]