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Some patients start with semaglutide because coverage is easier to obtain, then switch to tirzepatide if results plateau or if coverage changes

Alignment between outcomes and minimal clinically important differences in the Dutch type 2 diabetes mellitus guideline and healthcare professionals' preferences

Tirzepatide is administered subcutaneously once weekly at doses ranging from 2.5 mg to 15 mg, with gradual dose escalation recommended to minimize gastrointestinal adverse effects

doi: 10.1210/jcem-37-5-826 [DOI] [PubMed] [Google Scholar] 12
