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For others, discomfort worsens with dose increases

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As this happens, more information will become available about the side effects of treatment, including effects on erectile function.
Pharmacogenetic studies and meta-analyses support the role of polymorphisms in the SLC6A4 promoter region (5-HTTLPR) and related methylation patterns in moderating antidepressant response and risk of adverse effects, although effect sizes are modest and findings vary by ancestry and study design [25,26]

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A team of international researchers have now found non-diabetic patients taking glucagon-like peptide-1 receptor agonist (GLP-1 RA) drugs are at a higher risk of stomach paralysis, pancreatitis, and bowel obstructions, compared with those taking other weight loss medications