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In addition, the GLP-1R-mediated AMPK phosphorylation pathway can also optimize the muscle fiber types, improve glycogen storage and glucose uptake, further synergistically enhancing the athletic performance of skeletal muscle [19]
Its administration is typically via subcutaneous injection once weekly, and dosing in clinical trials has ranged from 0.5 mg to 12 mg, adjusted to optimize efficacy and tolerability
Severe side effects like pancreatitis or extreme dehydration can happen with either option during dose increases
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