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Monitor your blood sugar: If you have diabetes, keep track of your levels and discuss any significant changes with your doctor

This prolonged retention increases pressure, fullness, and discomfort, especially after larger, protein-dense, or high-fat meals, even though digestion continues normally and food is not physically blocked. Large meal volume and gastric distension Larger meal volumes cause the stomach to stretch

In addition, GLP-1 contributes to the ileal brake, an inhibitory feedback loop designed to optimize the digestion and absorption of nutrients [48]

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GLP-1 Antidiabetic Medications Glucagon-like Peptide-1 (GLP-1) agonists are injectable medications used to treat Type 2 diabetes and may also cause weight loss

Zepbound holds FDA approval for chronic weight management and is delivered by injection, with no oral version of tirzepatide currently available for either the diabetes or weight-loss indication