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10.12890/2024_004357 11 JaacksL

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Rushing dose escalation increases side effects without proportionally increasing weight loss, and severe side effects can force dose reductions that effectively waste medication

References New England Journal of Medicine - Retatrutide Phase 2 Trial - Primary efficacy and safety data for retatrutide New England Journal of Medicine - SURMOUNT-1 Trial - Tirzepatide obesity trial results FDA - Zepbound (Tirzepatide) Approval - FDA approval information for tirzepatide ClinicalTrials.gov - Retatrutide Studies - Ongoing Phase 3 clinical trials ClinicalTrials.gov - Retatrutide Phase 3 trials Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice

The move is part of Lillys all hands on deck effort to ramp up supply of Zepbound and a similar drug for diabetes called Mounjaro amid widespread shortages, executive vice president Patrik Jonsson said in an interview