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doi: 10.1073/pnas.86.19.7606 [DOI] [PMC free article] [PubMed] [Google Scholar] 119

14 At least 900 participants were needed to start the trial intervention to ensure that at least 750 were randomized

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Rare cases of acute kidney injury have been reported in patients with severe dehydration or acute illness, reinforcing the importance of maintaining fluid intake and reporting fever, diarrhea, or vomiting to a healthcare provider immediately

Importantly, these decisions involve deeply personal considerations

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