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Selection strategy of dextran sulfate sodium-induced acute or chronic colitis mouse models based on gut microbial profile

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It has no meaningful connection to GLP-1 production or weight loss

Despite knowledge of obesity-related complications in younger adults (increased risk of type 2 diabetes, liver and cardiovascular disease and malignancy), these considerations may be outweighed, in older adults, by concerns regarding weight-loss induced reduction in skeletal muscle and bone mass, and the awareness of the obesity paradox