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Macro vascular complications are still the primary cause of death in patients with T2DM.Glucagon like peptide-1 receptor agonists (GLP1-RAs) are a new class of Injectable Anti-diabetes Agents (IADA) that provides blood glucose control with weight reduction ability, systolic blood pressure reduction and a noticeable improvement of lipid profile

The meta-analysis identified a nonsignificant increase of 2.4 bpm (95% CI 0.24, 5.05) with GLP-1RA treatment relative to placebo

An assessment of adverse effects of vildagliptin versus comparators on the liver, the pancreas, the immune system, the skin and in patients with impaired renal function from a large pooled database of Phase II and III clinical trials

Peptide manufacturing typically scales gradually throughout development: For many historical peptide drugs, that final step remained manageable within existing manufacturing infrastructure

Effects of liraglutide on myocardial function after cardiac surgery: a secondary analysis of the randomised controlled GLOBE trial

M., Killian, L., et al