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The results demonstrated a dose-dependent effect on weight loss, with the maximum reduction reaching 14.7%, compared to only 2.3% in the placebo group

Expert Commentary Disclaimer: The expert statements in this article reflect individual professional opinions and are provided for educational purposes only

Retatrutide extends the same class further as a triple receptor agonist, targeting the GLP-1, GIP, and glucagon receptors together, with the added glucagon activity aimed at boosting energy expenditure alongside appetite suppression

That is independence maintained longer
Our findings are consistent with previous studies showing additional metabolic-cardiovascular-renal benefits of combined GLP-1RA and SGLT2i use in patients with T2D 26 , and suggest a promising role for adding GLP-1RA to SGLT2i therapy in patients with MASLD

In addition, government initiatives aimed at improving chronic disease management, coupled with increasing investments by pharmaceutical companies, are positioning China as one of the fastest-growing markets for Glucagon-Like Peptide 1 (GLP-1) Agonists globally
