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Studies on treatment with GH secretagogues or GHRH for periods ranging from 20 weeks to 12 months did not report an increase in these mentioned side effects [16,17,18, 232]

The combined action of both pathways appears to result in enhanced glycaemic control and greater weight reduction than seen with GLP-1 agonism alone, as demonstrated in clinical trials

Summary by Stefan Botha

J Exp Biol 200(2):295302
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Peptides (2020) 125:170205