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Patients often need to meet certain health criteria, such as a diagnosis of obesity or a weight-related medical condition, like high blood pressure or prediabetes

The early phase focuses on allowing your body to adjust while minimizing potential side effects as your system adapts to this gradual metabolic change

And have a lot of fun doing it

(2016) published in Diabetes Care evaluated the addition of a DPP-4 inhibitor to existing GLP-1 receptor agonist therapy and found no significant additional reduction in HbA1c compared to GLP-1 agonist monotherapy

This combined effect helps lower blood sugar levels without raising the risk of hypoglycemia, which is low blood sugar

When individual components of MACE were analysed separately, GLP-1 RA reduced all three outcomes, with a more pronounced effect on stroke followed by cardiovascular death and myocardial infarction [253, 254]