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73 Hydration: Dehydration is a common, often overlooked cause of fatigue

The question becomes whether the potential for renewed medication sensitivity after a break justifies the risk of regaining weight during the off period

Whether retatrutide's additional glucagon and GIP receptor activity confers further hormonal benefits remains to be established in dedicated studies

That finding has significant implications

Around 59% of participants were living with high blood pressure, and the average treatment period was 66 weeks

From the clinical perspective, the advantage of this finding is that diabetics can receive a treatment based on activation of GLP-1R targeting their diabetes (i.e., antihyperglycemic), as well as improving the prognosis of stroke