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After a maximum 12-week screening phase, an anticipated 1840 patients in each trial are randomized (1:1) to semaglutide or placebo for 156 weeks (104-week main treatment phase and 52-week extension)

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Many studies nowadays talking about role of anti-diabetic drugs in cardiovascular diseases : ASCVD : -Beneficial : Metformin, SGLT2i, GLP ( mainly Albiglutide, Liraglutide, Semaglutide, Dulaglutide ), Thiazolidinediones TZD

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