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GLP-1 receptor agonists reduce intracranial pressure
Novo Nordisk ran a dedicated study of semaglutide plus a birth control pill containing ethinyl estradiol and levonorgestrel

(8) Excess body weight increases the mechanical load on weight-bearing joints, accelerating cartilage wear and joint degeneration, and contributing to a pro-inflammatory state that further exacerbates joint damage

doi: 10.1111/ANDR.13015 103 JensterleMPodbregarAGoricarKGregoricNJanezA

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Mechanistic studies confirm that GLP-1 receptor activation in the gastric fundus and pylorus reduces gastric motility and delays emptying