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Enteroendocrine L-cell derived peptide hormones, notably glucagon-like peptide-1 (GLP-1) and glucagon-like peptide-2 (GLP-2), have become important targets in the treatment of type 2 diabetes, obesity and intestinal diseases

It reveals the underlying disease biology again: hunger rises satiety falls energy expenditure stays suppressed the brain becomes more vulnerable to food reward central adiposity starts returning This is why obesity must be discussed like other chronic diseases
Those that do may see weight loss of 10% or more in a few months, and, if combined with a programme that helps you make long-term changes to your lifestyle, that weight loss can be greaterand can last far longer than weight-loss achieved through the usual fad diets

One previous study, published in JAMA, looked at data from nearly 1.

approximately 50% lower incidence of ovarian cancer
