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Semaglutide works by activating GLP-1 receptors in the brain and pancreas, slowing gastric emptying and reducing appetite signaling

Forcing yourself to finish the entire fruit can trigger nausea, vomiting, or gastrointestinal discomfort, so stopping when satisfied is essential

Lipases are gut enzymes that break down fat in your gut

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For individuals with established cardiovascular disease, strong family history, or multiple risk factors, lower targets (70-100 mg/dL for LDL cholesterol, below 80 mg/dL for ApoB) may be appropriate and have strong evidence supporting benefit