surpass cvot tirzepatide SURPASS-CVOT trial: was non-inferior to dulaglutide and superior to putative placebo for reducing the composite of CV death/HF events in patients with T2D and ASCVD. #AHA25 View the slides here: https://t.co/6VQpBHFP2I 🫀 EASD 2025: Tirzepatide (SURPASS-CVOT)

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GLP-1 RA use was consistently associated with improvements in headache frequency, weight reduction, and reduced need for acetazolamide or surgical interventions

The ANDAs seek approval for an in-house Sandoz generic version of the Tirzepatide autoinjector, a generic gastric inhibitory polypeptide receptor and GLP-1 RA

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FDA Tirzepatide dual agonism 72 -20%

Real-time measurements of dopamine via fiber photometry revealed specific dopamine changes in the nucleus accumbens at both the beginning and end of running bouts, with SG-treated animals showing amplified dopamine dynamics at these key behavioral timepoints