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It makes it easier to have lasting effects on your appetite, insulin sensitivity, and how your hormones work

Some practitioners use this as an introductory dose for patients who are particularly sensitive to GLP-1 side effects or who want to assess tolerance before committing to the standard titration

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Tissue changes develop over months

Semaglutide works for weight loss by mimicking the action of incretin, a natural gut hormone called GLP-1, and targeting GLP-1 receptors in the brain that control appetite and slow down how quickly the stomach empties, making you feel fuller for longer