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The physiologic role of GLP-1 receptors in the control of metabolic functions (Figure 2) has often been studied in rodents, following intracerebroventricular (icv) infusions of GLP-1 (7-36)-amide, or its analogues such as exendin-4 that are resistant to enzyme degradation (by NEP and DPP-4) [31]

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This hypothesis is consistent with neurobiological models proposing that excessive eating and substance use disorders stem from a common mechanism: the attribution of excessive incentive salience to reward-related cues (Berridge et al., 2010

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The research, published Thursday in JAMA Ophthalmology, found that after one year, more than twice as many people on GLP-1 drugs developed neovascular age-related macular degeneration compared to similar people who were not taking the drugs

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Making sense of the sensory regulation of hunger neurons

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Liraglutide for managing overweight and obesity TA664

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