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GLP-1 evolved to exert rapid transient effects to blunt postprandial glucose excursions, with a plasma half-life of a few minutes 3234 , and is highly susceptible to enzymatic degradation 3537

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The quality of each included RCT was assessed by the Cochrane Risk-of-Bias Tool 1.0

Washout Periods After administration of glucocorticoids, an Adverse Analytical Finding (positive doping test) can be reached for different periods of time after administration, depending on the glucocorticoid administered and the dose