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[DOI] [PMC free article] [PubMed] [Google Scholar] 95.Honka H, Koffert J, Hannukainen JC, Tuulari JJ, Karlsson HK, Immonen H, Oikonen V, Tolvanen T, Soinio M, Salminen P, Kudomi N, Mari A, Iozzo P, Nuutila P
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In general terms, phase II trials are of shorter duration since they are meant to provide an efficacy signal before proceeding to a pivotal trial
Some pharmacokinetic studies have examined the lower end of the dose-response curve, but these were conducted to establish appropriate starting doses for titration, not to validate microdosing as a standalone strategy
Trulicity is a glucagon like peptide-1 receptor analog (GLP-1 RA)
