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Nighttime reflux may worsen sleep and raise aspiration risk for those with obstructive sleep apnea

In the context of AITD, insulin resistance has been associated with higher titers of thyroid autoantibodies and more rapid progression to overt hypothyroidism [5]

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According to FDA-approved prescribing information, gastrointestinal adverse effects occur commonly with these medications, with nausea reported in 16-44% of patients, vomiting in 6-24%, and abdominal pain or distension in 5-18%, depending on the specific medication and dosage