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Appetite suppression is strong but the initial GI effects have subsided

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OTC PPIs can be taken daily for up to two weeks

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If youre struggling with weight gain despite eating well and staying active, the issue may not be your effort, it may be hormonal resistance

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Some individuals sensitive to coffee and Wegovy side effects may prefer reducing caffeine intake around injection day if digestive symptoms become more noticeable

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Orforglipron is now FDA-approved as Foundayo (approved April 1, 2026) and is available through LillyDirect, telehealth providers, and US retail pharmacies

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For patients considering semaglutide or already taking it, this information is critical

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