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Authorship All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this article, take responsibility for the integrity of the work as a whole and have given their approval for this version to be published

Amylin: pharmacology, physiology, and clinical potential

The Food Standards Agency (FSA) advises healthy adults not to take more than 70mg of CBD per day unless under medical supervision

Beyond GLP-1: Multi-Pathway Metabolic Support GlucoVantage's benefits extend beyond just GLP-1 activation: Improved Insulin Sensitivity : By activating AMPK (a critical metabolic regulator), dihydroberberine helps optimize insulin function, supporting healthy blood sugar levels and reducing fat storage

doi:10.1007/s43441-025-00764-4

Specification and emulation of the reference trial including our expansion studies are stated in the Supplementary Information, following the TrAnsparent ReportinG of observational studies Emulating a Target trial (TARGET) guideline (Supplementary Tables 2729) 42