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Description
An optimized GLP-1/CCK fusion had enhanced efficacy to lower body weight in obese rodents relative to mono-agonist controls and their co-administration [946,947]
GLP-1-based therapies for diabetes, obesity and beyond
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In multivariable models adjusting for age and sex, the odds of ION remained significantly higher with Wegovy compared with Ozempic, with ION risk being three times greater in men than in women
10.1016/j.exger.2013.02.005 29 Wegovy FDA (2019)
This finding directly contradicts other studies showing protective effects
