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Lastly, the systemic effects of GLP-1RAs, such as body weight loss [103] and potential reduction in muscle mass [104], pose significant challenges for elderly individuals with neurodegenerative diseases
Oil red O lipid droplets positive area reduced compared to the Vehicle group (Figure 8B)

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Assessment parameters included GLP-1R expression, amyloid plaque density, neuroinflammatory markers, neuronal apoptosis, and markers of brain glucose metabolism

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