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In February 2025, the FDA officially ended the drug shortage of semaglutide, significantly shifting the legality of compounded semaglutide
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GLP-1RAs with proven CV benefit are specifically recommended for use in people with T2D with high risk for cardiorenal disease or in those with established ASCVD
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Studies comparing the combined therapy to individual medications found greater reductions against SGLT2is than GLP1-RAs
